Blood Circulation in the Fetus and Newborn (2024)

How does the fetal circulatory system work?

During pregnancy, the fetal circulatory system works differently than after birth:

Blood Circulation in the Fetus and Newborn (1)

The fetal circulatory system uses two right to left shunts, which are small passages that direct blood that needs to be oxygenated. The purpose of these shunts is to bypass certain body parts? in particular, the lungs and liver ? that are not fully developed while the fetus is still in the womb. The shunts that bypass the lungs are called the foramen ovale, which moves blood from the right atrium of the heart to the left atrium, and the ductus arteriosus, which moves blood from the pulmonary artery to the aorta.

Oxygen and nutrients from the mother's blood are transferred across the placenta to the fetus. The enriched blood flows through the umbilical cord to the liver and splits into three branches. The blood then reaches the inferior vena cava, a major vein connected to the heart. Most of this blood is sent through the ductus venosus, also a shunt that passes highly oxygenated blood through the liver to the inferior vena cava and then to the right atrium of the heart. A small amount of this blood goes directly to the liver to give it the oxygen and nutrients it needs.

Waste products from the fetal blood are transferred back across the placenta to the mother's blood.

Inside the fetal heart:

  • Blood enters the right atrium, the chamber on the upper right side of the heart. When the blood enters the right atrium, most of it flows through the foramen ovale into the left atrium.

  • Blood then passes into the left ventricle (lower chamber of the heart) and then to the aorta, (the large artery coming from the heart).

  • From the aorta, blood is sent to the heart muscle itself in addition to the brain. After circulating there, the blood returns to the right atrium of the heart through the superior vena cava. About two thirds of the blood will pass through the foramen ovale as described above, but the remaining one third will pass into the right ventricle, toward the lungs.

  • In the fetus, the placenta does the work of breathing instead of the lungs. As a result, only a small amount of the blood continues on to the lungs. Most of this blood is bypassed or shunted away from the lungs through the ductus arteriosus to the aorta. Most of the circulation to the lower body is supplied by blood passing through the ductus arteriosus.

  • This blood then enters the umbilical arteries and flows into the placenta. In the placenta, carbon dioxide and waste products are released into the mother's circulatory system, and oxygen and nutrients from the mother's blood are released into the fetus' blood.

At birth, the umbilical cord is clamped and the baby no longer receives oxygen and nutrients from the mother. With the first breaths of life, the lungs begin to expand. As the lungs expand, the alveoli in the lungs are cleared of fluid. An increase in the baby's blood pressure and a significant reduction in the pulmonary pressures reduces the need for the ductus arteriosus to shunt blood. These changes promote the closure of the shunt. These changes increase the pressure in the left atrium of the heart, which decrease the pressure in the right atrium. The shift in pressure stimulates the foramen ovale to close.

The closure of the ductus arteriosus and foramen ovale completes the transition of fetal circulation to newborn circulation.

Blood Circulation in the Fetus and Newborn (2)

Blood Circulation in the Fetus and Newborn (2024)

FAQs

How is the circulation of a fetus different from the circulation of a baby? ›

In fetal circulation, the right side of the heart has higher pressures than the left side of the heart. This pressure difference allows the shunts to remain open. In postnatal circulation, when the baby takes its first breath, pulmonary resistance decreases, and blood flow through the placenta ceases.

What is the change from fetal to newborn circulation? ›

The transition from the fetal to the neonatal circulation thus includes elimination of the placental circulation, lung expansion, and increase in lung blood flow so that the entire cardiac output can be accommodated, and closure of the foramen ovale, ductus arteriosus, and ductus venosus.

What is the correct order of blood flow in fetal circulation? ›

Most of the blood flows to the left side through a special fetal opening between the left and right atria. This is called the foramen ovale. Blood then passes into the left ventricle (lower chamber of the heart). It then goes to the aorta (the large artery coming from the heart).

At what week does fetal circulation start? ›

In a developing embryo,the heart has developed enough by day 21 post-fertilization to begin beating. Circulation patterns are clearly established by the fourth week of embryonic life.

What is the difference between fetal and adult blood circulation? ›

The fetal circulation system is distinctly different from adult circulation. This intricate system allows the fetus to receive oxygenated blood and nutrients from the placenta. It is comprised of the blood vessels in the placenta and the umbilical cord, which contains two umbilical arteries and one umbilical vein.

What is a major difference between fetal blood flow? ›

In the fetus, the placenta does the work of breathing instead of the lungs. As a result, only a small amount of the blood continues on to the lungs. Most of this blood is bypassed or shunted away from the lungs through the ductus arteriosus to the aorta.

Does the mother's blood go into the baby? ›

Nutrients and oxygen from the mother's blood pass into the baby's bloodstream through the placenta. Meanwhile, the baby excretes carbon dioxide and waste products through the umbilical blood vessels. But the blood of the fetus and the blood of the mother never meet. The placenta handles the exchange.

Does the blood of the mother and the baby ever mix? ›

During the birth, though, the mother's and baby's blood can mix. If this happens, the mother's body recognizes the Rh protein as a foreign substance. It then might begin making antibodies (proteins that act as protectors if foreign cells enter the body) against the Rh protein.

What are the 4 structures of fetal circulation? ›

Adult Derivatives of Fetal Vascular Structures
Fetal StructureAdult Structure
Umbilical Vein (intra-abdominal part)Ligamentum teres
Ductus VenosusLigamentum venosum
Umbilical Arteries and abdominal ligamentsmedial umbilical ligaments, superior vesicular artery (supplies bladder)
Ductus ArteriosumLigamentum arteriosum
1 more row

Which organ is bypassed by the special circulation pathways of a fetus? ›

Circulating blood bypasses the lungs and liver by flowing in different pathways and through special openings called shunts. Blood flow in the unborn baby follows this pathway: Oxygen and nutrients from the mother's blood are transferred across the placenta to the fetus through the umbilical cord.

What week does baby connect to blood supply? ›

Week 4 - implantation

The outer cells reach out to form links with your blood supply.

How does a fetus get oxygen? ›

Share on Pinterest The umbilical cord provides a baby with oxygen-rich blood in the womb. After 5-6 weeks of pregnancy, the umbilical cord develops to deliver oxygen directly to the developing fetus's body. The umbilical cord connects to the placenta, which is connected to the uterus.

How does fetal circulation differ from normal circulation quizlet? ›

Fetal circulation differs from adult circulation due to the presence of certain shunts and vessels. These shunts will close after birth and most of the vessels will be seen as remnants in the adult circulation. The lungs finish their development AFTER birth.

What is the difference between maternal and fetal circulation? ›

The in-flowing maternal arterial blood pushes deoxygenated blood into the endometrial and then uterine veins back to the maternal circulation. The fetal-placental circulation allows the umbilical arteries to carry deoxygenated and nutrient-depleted fetal blood from the fetus to the villous core fetal vessels.

What are the changes in circulation during pregnancy? ›

During pregnancy, a number of changes affecting venous blood flow occur in the circulatory system, such as reduced vein wall tension or increased exposure to collagen fibers. These factors may cause blood stagnation, swelling of the legs, or endothelial damage and consequently lead to development of venous disease.

What structures are unique to fetal circulation? ›

Three shunts in the fetal circulation
  • Ductus arteriosus. protects lungs against circulatory overload. allows the right ventricle to strengthen. ...
  • Ductus venosus. fetal blood vessel connecting the umbilical vein to the IVC. ...
  • Foramen ovale. shunts highly oxygenated blood from right atrium to left atrium.

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