Fetal macrosomia: Causes and complications of having a too-big baby (2024)

Having a baby who's bigger than average for their gestational age? Here's what to expect when it comes to fetal macrosomia.

What is fetal macrosomia?

Macrosomia means "large body" and is used to describe a newborn who's much larger than average. (The average newborn weighs about 7 pounds.)

There isn't a single definition for macrosomia. Historically, babies with macrosomia weigh more than 8 pounds, 13 ounces (4,000 grams) or more than 9 pounds, 15 ounces (4,500 grams) at birth. Macrosomic babies are more likely to have a difficult delivery. But the risk of complications is significantly greater when a baby is born weighing more than 9 pounds, 15 ounces.

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The Centers for Disease Control and Prevention (CDC) estimates that 6 percent of infants born in 2021 weighedbetween 8 pounds 13 ounces and 9 pounds 14 ounces at birth, and less than 1 percent weighed 9 pounds 15 ounces or more.

How will I know if my baby is macrosomic?

It's difficult to tell how big your baby is while they're still in the womb, but your healthcare provider may suspect macrosomia if you're measuring large for dates. Also, because bigger babies produce more amniotic fluid, excessive amniotic fluid (polyhydramnios) might be a sign.

What causes macrosomia?

Some women are just genetically predisposed to have larger babies, and birth weight also tends to increase with each successive pregnancy.

Most women who have a baby weighing more than 9 pounds have no risk factors, but macrosomia may be more likely if:

  • You have unmanaged high blood sugar levels from diabetes or gestational diabetes
  • You have obesity
  • You're tall
  • You've gained too much weight during pregnancy
  • You've already had a large baby. If you previously delivered a macrosomic baby, you're five to 10 times more likely to have another large baby.
  • You're more than two weeks past your due date
  • You were large for gestational age (LGA) yourself
  • You're over age 35
  • You have certain genetic abnormalities or syndromes (such as Sotos syndrome or Beckwith-Wiedemann syndrome

Also, male babies are more often macrosomic than females. And mothers who are white, American Indian, or Samoan are more likely to have macrosomic babies than women of other ethnicities. A study of mothers with gestational diabetes found that Latino women had macrosomic babies more often than Black women.

How does a big baby affect delivery?

With a big baby, you have a greater chance of a difficult vagin*l delivery. You may also have an increased risk of preterm birth, perineal tearing, and blood loss.

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Also, if you've had a previous C-section or major uterine surgery, a large baby would increase your risk of uterine rupture, a rare but dangerous complication.

A large baby also means you're more likely to have an assisted vagin*l delivery or a cesarean. Although it's difficult to determine a baby's exact size before birth, your doctor may want to schedule a C-section if you're measuring large or have other risk factors for macrosomia.

The American College of Obstetrics and Gynecologists (ACOG) doesn't recommendinducing labor early for suspected macrosomia, since this doesn't have any proven benefit.

Can macrosomia cause problems for my baby?

If your baby is macrosomic, there's a higher risk for birth injury and some complications. But most of the possible complications usually resolve with no long-term consequences.

There's a small chance of shoulder dystocia, a rare but potentially serious complication in which the baby's shoulder gets caught behind your pubic bone, causing the baby to get stuck in the birth canal during delivery.

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This situation is a medical emergency. Your healthcare provider will need to do some maneuvering or perform an episiotomy to get your baby out safely.

In rare cases, your baby could end up with a broken collarbone or upper arm bone. (The treatment is to immobilize the arm as much as possible until the fracture heals.) A more serious complication of shoulder dystocia is nerve damage to the arm on the side where the shoulder was trapped.

A macrosomic baby is also at higher risk for:

  • Low blood sugar
  • Lower Apgar score
  • Childhood obesity
  • Metabolic syndrome in childhood, which can increase the risk of heart disease, diabetes, and stroke.
  • Breathing problems immediately after birth

What is recovery like after giving birth to a big baby?

If you had a perineal tear or an episiotomy, be sure to follow your provider's instructions for perineal care, and watch for signs of infection.

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If you had gestational diabetes, your blood glucose levels should return to normal after birth. But you still have an increased risk of developing diabetes in the future, so within a few months of your baby's birth, schedule a follow-up appointment with your provider to be tested for postpartum diabetes or other problems with glucose metabolism.

Can I prevent macrosomia?

There are things you can do to reduce the risk:

  • Start pregnancy at a healthy weight if possible. Try to lose weight before becoming pregnant if you're overweight.
  • Do your best to maintain a healthy pregnancy weight.
  • If you have diabetes or develop gestational diabetes, stick to your provider's recommendations to control your blood sugar.

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Fetal macrosomia: Causes and complications of having a too-big baby (2024)

FAQs

Fetal macrosomia: Causes and complications of having a too-big baby? ›

Maternal risks

Possible maternal complications of fetal macrosomia might include: Labor problems. Fetal macrosomia can cause a baby to become wedged in the birth canal (shoulder dystocia), sustain birth injuries, or require the use of forceps or a vacuum device during delivery (operative vagin*l delivery).

What are the complications of macrosomia baby? ›

Maternal risks

Possible maternal complications of fetal macrosomia might include: Labor problems. Fetal macrosomia can cause a baby to become wedged in the birth canal (shoulder dystocia), sustain birth injuries, or require the use of forceps or a vacuum device during delivery (operative vagin*l delivery).

What is macrosomia quizlet? ›

- Macrosomia = growth beyond a specific weight, usually 4,000 g or 4,500 g, regardless of the gestational age.

What are the risks of having a big baby? ›

Having a large baby can increase your risk for certain complications during childbirth. Some of the most common include: Injury to your birth canal, genital tract or perineum. Heavy bleeding or postpartum hemorrhage.

What disease of pregnancy causes a baby to be too large when born? ›

Babies are called large for gestational age if they weigh more than expected for their gestational age (weeks of pregnancy) at birth. Diabetes is the most common cause of babies who are large for gestational age. If a baby is too large to fit through the birth canal easily, delivery can be difficult.

What causes fetal overgrowth? ›

Overgrowth syndromes are caused by gene mutations or abnormalities. The exact genetic cause is sometimes unknown. In some children the overgrowth may be the result of an inherited gene change, while other children have a new gene change with no family history.

What syndrome is associated with fetal macrosomia? ›

Certain genetic and congenital disorders are associated with an increased risk of macrosomia, including Beckwith-Weidemann syndrome, Sotos syndrome, fragile X syndrome, and Weaver syndrome.

What is the difference between macrosomia and big baby? ›

Infants whose weight is > the 90th percentile for gestational age are classified as large for gestational age. Macrosomia is birthweight > 4000 g in a term infant. The predominant cause is maternal diabetes. Complications include birth trauma, hypoglycemia, hyperviscosity, and hyperbilirubinemia.

What are the genetic causes of macrosomia? ›

Fetal causes

Causes of fetal macrosomia associated with the fetus include : Beckwith-Wiedemann syndrome: This is an overgrowth condition that affects specific chromosomes. Sotos syndrome: This is a rare genetic disorder that results from a mutation in the NSD1 gene.

What fetal size is macrosomia? ›

A fetus larger than 4000 to 4500 grams (or 9 to 10 pounds) is considered macrosomic. Macrosomia is associated with an increased risk of several complications, particularly maternal and/or fetal trauma during birth and neonatal hypoglycemia and respiratory problems.

What happens if your baby is measuring big? ›

Most babies that are LGA pose minimal risk and are delivered normally with no complications, however it is important that women are aware of any increase of risk involved, these include: An increased chance of having a caesarean section or instrumental birth may be needed.

What are the complications of large for gestational age? ›

Large size itself increases risk of birth injury (eg, clavicle or extremity long bone fracture) and perinatal asphyxia. Infants of mothers with diabetes also may have metabolic complications immediately after delivery, including hypoglycemia, hypocalcemia, and polycythemia.

How big is too big to birth? ›

If there's any doubt — especially if baby looks like he or she will be over 10 pounds at birth — your doctor will probably recommend a c-section over a vagin*l delivery. But there are also other factors that come into play when determining whether you'll be able to deliver vagin*lly or through a c-section.

What are 5 complications of macrosomia? ›

In this article, we present a case of a neonate born at >5 kg who experienced many of the complications of neonatal macrosomia including hypoglycemia, convulsions, respiratory distress syndrome, sepsis, laryngotracheomalacia, and Ebbs palsy due to birth trauma, hypoxic‐ischemic encephalopathy, and polycythemia.

What is one of the strongest risk factors for macrosomia? ›

Genetic, sex, racial, and ethnic factors influence birth weight and the risk of macrosomia. Male newborns typically weigh more than female newborns and thus comprise a greater proportion of infants with birth weights exceeding 4500 g. The risk of macrosomia also varies with ethnicity.

Can macrosomia cause stillbirth? ›

Conclusion. Extremes of fetal growth are associated with increased risk of stillbirth. Increased risk of stillbirth in macrosomia is independent of diabetes and other complications of pregnancy.

What are the risks of high birth weight babies? ›

The perinatal outcomes for babies of high birth weight and being LGA are mainly associated with difficulties at delivery such as asphyxia, shoulder dystocia, hypoglycemia, respiratory problems, cesarean section, and obstetric injuries (12, 13).

What are the neonatal outcomes of macrosomia? ›

The results showed that macrosomic infants had higher rates of hypoglycemia, transient tachypnea of the newborn, hyperthermia, and birth trauma.

Does macrosomia affect brain? ›

Intriguingly, macrosomic females had both increased blood pressures and reduced brain weight. Neonatal brain growth and development is known to display strong sexual dimorphism [25].

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